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https://dora.health.qld.gov.au/qldresearchjspui/handle/1/5174| Title: | Effect of Vancomycin or Daptomycin With vs Without an Antistaphylococcal β-Lactam on Mortality, Bacteremia, Relapse, or Treatment Failure in Patients With MRSA Bacteremia: A Randomized Clinical Trial | Authors: | Tong, Steven Y C Lye, David C Yahav, Dafna Sud, Archana Robinson, J Owen Nelson, Jane Archuleta, Sophia Roberts, Matthew A Cass, Alan Paterson, David L Foo, Hong Paul, Mical Guy, Stephen D Tramontana, Adrian R Walls, Genevieve B McBride, Stephen Bak, Narin Ghosh, Niladri Rogers, Benjamin A Ralph, Anna P Davies, Jane Ferguson, Patricia E Dotel, Ravindra McKew, Genevieve L Gray, Timothy J Holmes, Natasha E Smith, Simon Warner, Morgyn S Kalimuddin, Shirin Young, Barnaby E Runnegar, Naomi Andresen, David N Anagnostou, Nicholas A Johnson, Sandra A Chatfield, Mark D Cheng, Allen C Fowler, Vance G Howden, Benjamin P Meagher, Niamh Price, David J van Hal, Sebastiaan J O'Sullivan, Matthew V N Davis, Joshua S |
Issue Date: | 2020 | Publisher: | American Medical Association | Source: | Tong, S. Y. C., Lye, D. C., Yahav, D., Sud, A., Robinson, J. O., Nelson, J., Archuleta, S., Roberts, M. A., Cass, A., Paterson, D. L., Foo, H., Paul, M., Guy, S. D., Tramontana, A. R., Walls, G. B., McBride, S., Bak, N., Ghosh, N., Rogers, B. A., Ralph, A. P., … Australasian Society for Infectious Diseases Clinical Research Network (2020). Effect of Vancomycin or Daptomycin With vs Without an Antistaphylococcal β-Lactam on Mortality, Bacteremia, Relapse, or Treatment Failure in Patients With MRSA Bacteremia: A Randomized Clinical Trial. JAMA, 323(6), 527–537. https://doi.org/10.1001/jama.2020.0103 | Journal: | JAMA | Abstract: | Methicillin-resistant Staphylococcus aureus (MRSA) bacteremia is associated with mortality of more than 20%. Combining standard therapy with a β-lactam antibiotic has been associated with reduced mortality, although adequately powered randomized clinical trials of this intervention have not been conducted. | Description: | Cairns & Hinterland Hospital and Health Service (CHHHS) affiliated author: Simon Smith | DOI: | 10.1001/jama.2020.0103 | Type: | Article |
| Appears in Sites: | Cairns & Hinterland HHS Publications |
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| File | Description | Size | Format | |
|---|---|---|---|---|
| Effect of Vancomycin or Daptomycin with vs without an antistaphylococcal B-Lactam.pdf | 434.1 kB | Adobe PDF |  View/Open |
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