Please use this identifier to cite or link to this item: https://dora.health.qld.gov.au/qldresearchjspui/handle/1/1765
Title: Potentially preventable dementia in a First Nations population in the Torres Strait and Northern Peninsula Area of North Queensland, Australia: A cross sectional analysis using population attributable fractions
Authors: Thompson, Fintan 
Sarah Russell
Quigley, Rachel 
Betty Sagigi
Sean Taylor
Malcolm McDonald
Campbell, Sandy 
Adrian Esterman
Harriss, Linton 
Miller, Gavin 
Strivens, Edward 
Robyn McDermott
Issue Date: 2022
Publisher: Elsevier
Source: Thompson F, Russell S, Quigley R, Sagigi B, Taylor S, McDonald M, Campbell S, Esterman A, Harriss LR, Miller G, Strivens E, McDermott R. Potentially preventable dementia in a First Nations population in the Torres Strait and Northern Peninsula Area of North Queensland, Australia: A cross sectional analysis using population attributable fractions. Lancet Reg Health West Pac. 2022 Jul 6;26:100532. doi: 10.1016/j.lanwpc.2022.100532. PMID: 35833207; PMCID: PMC9272378.
Journal: The Lancet regional health. Western Pacific
Abstract: Dementia is highly prevalent among Australia's First Nations peoples, including Torres Strait Islander and Aboriginal peoples in Far North Queensland (FNQ). It is likely that historically recent exposure to modifiable risk factors underlies these rates, and a large proportion of dementia may be potentially preventable. Data from two adult community health checks (2015-2018) were analyzed to determine the prevalence of 11 modifiable dementia risk factors among the First Nations residents of the Torres Strait and Northern Peninsula Area of FNQ. Population attributable fractions (PAF%) for dementia were calculated using age-standardized prevalence estimates derived from these health checks and relative risks obtained from previous meta-analyses in other populations. PAF% estimates were weighted for communality to account for overlap of risk factors. Half (52·1%) of the dementia burden in this population may be attributed to 11 potentially modifiable risk factors. Hypertension (9·4%), diabetes mellitus (9·0%), obesity (8·0%), and smoking (5·3%) were the highest contributing risk factors. The contribution of depression (2·0%) and alcohol (0·3%) was lower than other global and national estimates. While the adjusted PAF% for social isolation was low based on the adult community health check data (1·6%), it was higher (4·2%) when official census data were analyzed. These results suggest that a substantial proportion of dementia in FNQ First Nations peoples could potentially be prevented. Government investment in preventative health now is essential to reduce the future burden of dementia. National Health and Medical Research Council (NHMRC, GNT1107140, GNT1191144, GNT1106175, GNT0631947).
Description: Cairns & Hinterland Hospital and Health Service (CHHHS) affiliated authors: Sarah Russell, Rachel Quigley, Linton R Harriss, Gavin Miller, Edward Strivens
DOI: 10.1016/j.lanwpc.2022.100532
Keywords: Dementia;Prevention;First Nations;Indigenous;Population attributable fractions;Australia
Type: Article
Appears in Sites:Cairns & Hinterland HHS Publications

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