Please use this identifier to cite or link to this item: https://dora.health.qld.gov.au/qldresearchjspui/handle/1/5415
Full metadata record
DC FieldValueLanguage
dc.contributor.authorButler, Jessicaen
dc.contributor.authorGunnarsson, Ronnyen
dc.contributor.authorTraves, Aileenen
dc.contributor.authorMarshall, Helenen
dc.date.accessioned2023-10-31T05:29:39Z-
dc.date.available2023-10-31T05:29:39Z-
dc.date.issued2019-
dc.identifier.citationButler J, Gunnarsson R, Traves A, Marshall H. Severe Respiratory Syncytial Virus Infection in Hospitalized Children Less Than 3 Years of Age in a Temperate and Tropical Climate. Pediatr Infect Dis J. 2019 Jan;38(1):6-11. doi: 10.1097/INF.0000000000002026. PMID: 30531526.en
dc.identifier.urihttps://dora.health.qld.gov.au/qldresearchjspui/handle/1/5415-
dc.descriptionCairns & Hinterland Hospital and Health Service (CHHHS) affiliated authors: Ronny Gunnarsson, Aileen Travesen
dc.description.abstractRespiratory syncytial virus (RSV) infection is a frequent cause of hospitalization in infants younger than 3 years of age. We aimed to determine the factors associated with severe RSV disease. Retrospective medical review of children up to 3 years of age admitted for laboratory-proven RSV infection between January 1, 2013, and December 31, 2014, was conducted at the Women's and Children's Hospital, Adelaide, South Australia, and the Paediatric Department at Cairns Hospital, Cairns, North Queensland. Severity of infection was determined using the validated Brisbane RSV Infection Severity Score. Four-hundred ninety-six children (383 at Women's and Children's Hospital and 113 at Cairns Hospital) were included in the study, with 76, 323 and 97 patients identified as having mild, moderate or severe disease, respectively. Decreasing age [odds ratio (OR) = 0.95; 95% confidence interval (CI) = 0.90-0.99, P = 0.020), and being Indigenous, increased (OR = 2.6; 95% CI = 1.4-4.9, P = 0.002) the risk of severe RSV infection in hospitalized children. Underlying respiratory (P = 0.029, OR = 2.5; 95% CI = 1.1-5.8) or cardiac (OR = 2.7; 95% CI = 1.1-6.4, P = 0.024) conditions, as well as the presence of tachypnoea on admission (OR = 2.2; 95% CI = 1.2-4.1, P = 0.009), were also independent predictors of severe RSV infection. Seasonal variation in hospitalization was observed between temperate and tropical climates but was not associated with disease severity. Young infants, Indigenous patients and children with underlying respiratory and cardiac disease should be observed closely for signs of deterioration. Infants with tachypnoea on admission should be continuously monitored.en
dc.language.isoenen
dc.relation.ispartofThe Pediatric infectious disease journalen
dc.subjectrespiratory syncytial virusen
dc.subjectsevere diseaseen
dc.subjectpaediatricsen
dc.subjecthospitalizationen
dc.subjectbronchiolitisen
dc.titleSevere Respiratory Syncytial Virus Infection in Hospitalized Children Less Than 3 Years of Age in a Temperate and Tropical Climateen
dc.typeArticleen
dc.identifier.doi10.1097/INF.0000000000002026-
dc.identifier.pmid30531526-
item.fulltextNo Fulltext-
item.grantfulltextnone-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.languageiso639-1en-
item.openairetypeArticle-
Appears in Sites:Cairns & Hinterland HHS Publications
Show simple item record

Page view(s)

48
checked on Dec 23, 2024

Google ScholarTM

Check

Altmetric


Items in DORA are protected by copyright, with all rights reserved, unless otherwise indicated.