Please use this identifier to cite or link to this item: https://dora.health.qld.gov.au/qldresearchjspui/handle/1/5190
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dc.contributor.authorHamdoon, Saifen
dc.contributor.authorWilson, Ianen
dc.contributor.authorSmith, Simonen
dc.contributor.authorGericke, Christianen
dc.date.accessioned2023-06-14T02:13:00Z-
dc.date.available2023-06-14T02:13:00Z-
dc.date.issued2020-
dc.identifier.citationHamdoon, S., Wilson, I., Smith, S., & Gericke, C. (2020). Melioidosis of the nervous system: atypical presentation of a rare disease in a 48-year-old man. BMJ case reports, 13(11), e233498. https://doi.org/10.1136/bcr-2019-233498en
dc.identifier.urihttps://dora.health.qld.gov.au/qldresearchjspui/handle/1/5190-
dc.descriptionCairns & Hinterland Hospital and Health Service (CHHHS) affiliated authors: Saif Hamdoon, Ian Wilson, Simon Smithen
dc.description.abstractA 48-year-old man who worked in mining in remote, northern Australia was transferred from a rural hospital 5 days after the onset of headaches, subjective fevers and flaccid paralysis of the left upper limb. Initial investigations demonstrated inflammatory cerebrospinal fluid (CSF) changes and a longitudinally extensive cervical cord lesion. Given two serial negative blood and CSF cultures, he was treated as inflammatory myelitis with intravenous methylprednisolone. Despite the initial improvement in pain and left arm power, the patient's neurological deficit plateaued and then deteriorated with worsening neck pain, diaphragmatic dysfunction and dysphagia requiring intubation and respiratory support. A third CSF culture isolated Burkholderia pseudomallei confirming a diagnosis of neuro-melioidosis. Repeat imaging revealed the rostral extension of the original spinal cord lesion into the medulla and pons. Over the next 4 weeks, the patient's neurological deficits slowly improved with continued intravenous antibiotic therapy with meropenem and oral trimethoprim/sulfamethoxazole.en
dc.language.isoenen
dc.relation.ispartofBMJ Case Reportsen
dc.subjecttropical medicine (infectious disease)en
dc.subjectinfection (neurology)en
dc.subjectspinal corden
dc.titleMelioidosis of the nervous system: atypical presentation of a rare disease in a 48-year-old manen
dc.typeArticleen
dc.identifier.doi10.1136/bcr-2019-233498-
dc.identifier.pmid33148566-
item.fulltextNo Fulltext-
item.grantfulltextnone-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.languageiso639-1en-
item.openairetypeArticle-
Appears in Sites:Cairns & Hinterland HHS Publications
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