Please use this identifier to cite or link to this item: https://dora.health.qld.gov.au/qldresearchjspui/handle/1/5096
Title: Investigating the therapeutic options for diabetes-associated male infertility as illustrated in animal experimental models
Authors: Tsampoukas, Georgios 
Tharakan, Tharu 
Narayan, Yash 
Khan, Faisal 
Cayetano, Axel 
Papatsoris, Athanasios 
Buchholz, Noor 
Minhas, Suks 
Issue Date: 2022
Source: Tsampoukas, G., Tharakan, T., Narayan, Y., Khan, F., Cayetano, A., Papatsoris, A., Buchholz, N., & Minhas, S. (2022). Investigating the therapeutic options for diabetes-associated male infertility as illustrated in animal experimental models. Andrologia, 54(9), e14521. https://doi.org/10.1111/and.14521
Journal: Andrologia
Abstract: Diabetes is a rising global health concern and an increasingly common cause of male infertility. Although the definitive pathophysiological mechanisms underpinning the association between diabetes and infertility is unclear, there are several animal studies showing diabetes to be a detrimental factor on reproductive health through apoptosis, oxidative stress and impairment of steroidogenesis. Furthermore, as reflected in animal models, antidiabetic strategies and relevant treatments are beneficial in the management of infertile men with diabetes as the recovery of euglycemic status affects positively the spermatogenesis. However, the available data are still evolving and specific conclusion in human populations are not possible yet. In this review, we are discussing the current literature concerning the association of diabetes and male infertility, focusing on the therapeutic approach as illustrated in animals' models.
Description: Cairns & Hinterland Hospital and Health Service (CHHHS) affiliated author: Yash Narayan
DOI: 10.1111/and.14521
Keywords: animals;diabetes;male infertility
Type: Article
Appears in Sites:Cairns & Hinterland HHS Publications

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