Please use this identifier to cite or link to this item: https://dora.health.qld.gov.au/qldresearchjspui/handle/1/4837
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dc.contributor.authorRaman, S.en
dc.contributor.authorBrooks, J.en
dc.contributor.authorWilliams, T.en
dc.contributor.authorPham, T.en
dc.contributor.authorHarkins, M.en
dc.contributor.authorPegg, D.en
dc.contributor.authorDunster, K.en
dc.contributor.authorAlphonso, N.en
dc.contributor.authorGibbons, K.en
dc.contributor.authorSchibler, A.en
dc.date.accessioned2022-11-07T23:56:46Z-
dc.date.available2022-11-07T23:56:46Z-
dc.date.issued2021en
dc.identifier.citation22, (SUPPL 1), 2021, p. 195-196en
dc.identifier.otherRISen
dc.identifier.urihttp://dora.health.qld.gov.au/qldresearchjspui/handle/1/4837-
dc.description.abstractAIMS & OBJECTIVES: Few studies have evaluated accuracy and precision of SpO2 in children, although sensor manufacturers claim high sensitivity, specificity and accuracy. This study aims to evaluate the performance of pulse oximetry in critically ill paediatric patients, quantify the bias between SpO2 and SaO2, determine the sensitivity and specificity to detect true hypoxaemia. METHODS: This observational study paired SpO2 readings obtained with a Masimo and a Nellcor sensor and prospectively matched and validated them to the arterial haemoglobin oxygen saturation (SaO2). Bias between SpO2 and SaO2 (SpO2-SaO2), accuracy root mean square (Arms), sensitivity, specificity and kappa agreement were calculated for sensors. Multivariable regression analysis was conducted to determine the relationship between clinical variables and bias in paired sensor readings. This study was conducted in a 36-bed mixed medical/surgical paediatric intensive care unit. All children <16 years old with an arterial line were eligible. RESULTS: There were 929 participants with 16,839 readings (9,382 simultaneous Masimo and Nellcor). Nineteen percent of paired values had SaO2<88%. Bias increased with decreasing SaO2. Both sensors failed to achieve FDA's Arms requirement in all ranges. Of the 15.5% patients with 'true hypoxaemia' (SaO2<88%), 28.6% (n=1165) were not correctly identified by pulse oximetry. Variables associated with higher odds of bias included sepsis, respiratory distress and post-cardiac arrest; increasing lactate; vasoconstrictor use; lower SaO2and low admission weight. CONCLUSIONS: Both tested sensors, with current algorithms, are not precise enough for a PICU setting. Sensor readings in patients with respiratory disease, sepsis and cardiac arrest should be used with caution.L6347728052021-04-21 <br />en
dc.language.isoenen
dc.relation.ispartofPediatric Critical Care Medicineen
dc.titleTranscutaneous oxygen saturation accuracy in critically ill childrenen
dc.typeArticleen
dc.identifier.doi10.1097/01.pcc.0000739828.15966.00en
dc.subject.keywordssensoren
dc.subject.keywordssepsisen
dc.subject.keywordsquantitative analysisen
dc.subject.keywordsendogenous compoundhemoglobinen
dc.subject.keywordslactic aciden
dc.subject.keywordsvasoconstrictor agenten
dc.subject.keywordsalgorithmen
dc.subject.keywordsarterial lineen
dc.subject.keywordsarterial oxygen saturationen
dc.subject.keywordschilden
dc.subject.keywordsconference abstracten
dc.subject.keywordscontrolled studyen
dc.subject.keywordscritically ill patienten
dc.subject.keywordsfemaleen
dc.subject.keywordsheart arresten
dc.subject.keywordshumanen
dc.subject.keywordshypoxemiaen
dc.subject.keywordsmajor clinical studyen
dc.subject.keywordsmaleen
dc.subject.keywordsobservational studyen
dc.subject.keywordspediatric intensive care uniten
dc.subject.keywordspediatric patienten
dc.subject.keywordspulse oximeteren
dc.subject.keywordsrespiratory distressen
dc.subject.keywordssensitivity and specificityen
dc.relation.urlhttps://www.embase.com/search/results?subaction=viewrecord&id=L634772805&from=exporthttp://dx.doi.org/10.1097/01.pcc.0000739828.15966.00 |en
dc.identifier.risid587en
dc.description.pages195-196en
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.fulltextNo Fulltext-
item.grantfulltextnone-
item.openairetypeArticle-
item.languageiso639-1en-
Appears in Sites:Children's Health Queensland Publications
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