Please use this identifier to cite or link to this item: https://dora.health.qld.gov.au/qldresearchjspui/handle/1/4709
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dc.contributor.authorJusto, R.en
dc.contributor.authorAyer, J.en
dc.contributor.authorGrigg, L.en
dc.contributor.authorClendenning, C.en
dc.contributor.authorHornung, T.en
dc.contributor.authorDavis, G. M.en
dc.contributor.authorCordina, R.en
dc.contributor.authord'Udekem, Y.en
dc.contributor.authorTran, D. L.en
dc.contributor.authorCelermajer, D. S.en
dc.date.accessioned2022-11-07T23:55:33Z-
dc.date.available2022-11-07T23:55:33Z-
dc.date.issued2021en
dc.identifier.citation8 , 2021, p. 764273en
dc.identifier.otherRISen
dc.identifier.urihttp://dora.health.qld.gov.au/qldresearchjspui/handle/1/4709-
dc.description.abstractBackground: People with a Fontan circulation usually have moderately impaired exercise performance, although a subset have high physical performance ("Super-Fontan"), which may represent a low-risk phenotype. Methods: People with a "Super-Fontan" phenotype were defined as achieving normal exercise performance [≥80% predicted peak oxygen uptake (VO(2)) and work rate] during cardiopulmonary exercise testing (CPET) and were identified from the Australian and New Zealand Fontan Registry. A Fontan control group that included people with impaired exercise performance (<80% predicted VO(2) or work rate) was also identified based on a 1:3 allocation ratio. A subset of participants were prospectively recruited and completed a series of physical activity, exercise self-efficacy, and health-related quality of life questionnaires. Results: Sixty CPETs ("Super-Fontan", n = 15; control, n = 45) were included. A subset ("Super-Fontan", n = 10; control, n = 13) completed a series of questionnaires. Average age was 29 ± 8 years; 48% were males. Exercise capacity reflected by percent predicted VO(2) was 67 ± 17% in the entire cohort. Compared to the "Super-Fontan" phenotype, age at Fontan completion was higher in controls (4.0 ± 2.9 vs. 7.2 ± 5.3 years, p = 0.002). Only one (7%) person in the "Super-Fontan" group had a dominant right ventricle compared to 15 (33%) controls (p = 0.043). None of those in the "Super-Fontan" group were obese, while almost a quarter (22%) of controls were obese based on body mass index (p = 0.046). Lung function abnormalities were less prevalent in the "Super-Fontan" group (20 vs. 70%, p = 0.006). Exercise self-efficacy was greater in the "Super-Fontan" group (34.2 ± 3.6 vs. 27.9 ± 7.2, p = 0.02). Self-reported sports participation and physical activity levels during childhood and early adulthood were higher in the "Super-Fontan" group (p < 0.05). The total average time spent participating in structured sports and physical activity was 4.3 ± 2.6 h/wk in the "Super-Fontan" group compared to 2.0 ± 3.0 h/wk in controls, p = 0.003. There were no differences in self-reported current total physical activity score or health-related quality of life between groups (p ≥ 0.05). Conclusions: The "Super-Fontan" phenotype is associated with a healthy weight, lower age at Fontan completion, better exercise self-efficacy, and higher overall levels of sport and physical activity participation during physical development.2297-055xTran, Derek L <br />Celermajer, David S <br />Ayer, Julian <br />Grigg, Leeanne <br />Clendenning, Carley <br />Hornung, Tim <br />Justo, Robert <br />Davis, Glen M <br />d'Udekem, Yves <br />Cordina, Rachael <br />Journal Article <br />Front Cardiovasc Med. 2021 Dec 7;8:764273. doi: 10.3389/fcvm.2021.764273. eCollection 2021. <br />en
dc.language.isoenen
dc.relation.ispartofFront Cardiovasc Meden
dc.titleThe "Super-Fontan" Phenotype: Characterizing Factors Associated With High Physical Performanceen
dc.typeArticleen
dc.identifier.doi10.3389/fcvm.2021.764273en
dc.subject.keywordsconflict of interest.en
dc.subject.keywordsphysical activityen
dc.subject.keywordsexercise trainingen
dc.subject.keywordsexercise capacityen
dc.subject.keywordscardiac rehabilitationcongenital heart diseaseen
dc.subject.keywordscommercial or financial relationships that could be construed as a potentialen
dc.identifier.risid3087en
dc.description.pages764273en
item.grantfulltextnone-
item.openairetypeArticle-
item.fulltextNo Fulltext-
item.languageiso639-1en-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
Appears in Sites:Children's Health Queensland Publications
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