Please use this identifier to cite or link to this item: https://dora.health.qld.gov.au/qldresearchjspui/handle/1/4063
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dc.contributor.authorRoberts, P.en
dc.contributor.authorLawley, C.en
dc.contributor.authorTanous, D.en
dc.contributor.authorAnderson, B.en
dc.contributor.authorCelermajer, D.en
dc.contributor.authorWilson, W.en
dc.contributor.authorShipton, S.en
dc.contributor.authorO'Donnell, C.en
dc.date.accessioned2022-11-07T23:48:55Z-
dc.date.available2022-11-07T23:48:55Z-
dc.date.issued2019en
dc.identifier.citation28 , 2019, p. S351-S352en
dc.identifier.otherRISen
dc.identifier.urihttp://dora.health.qld.gov.au/qldresearchjspui/handle/1/4063-
dc.description.abstractBackground: The ANZ population undergoing PPVI, including short to medium term outcomes, has not been fully characterised. In particular, there are concerns about infective endocarditis (IE) risk. Methods: A multi-site retrospective cohort study across seven centres in ANZ. PPVI cases were identified using institutional databases and relevant details collected. Key outcomes evaluated at follow-up included mortality, morbidity (repeat procedure, infective endocarditis) and echocardiographic data. Results: From June 2009-March 2018, 134 individuals underwent PPVI utilising 123 Medtronic Melody™ valves and 11 Edwards SAPIEN valves (median age 18 years, range 9–60 years; median weight 59 kg, range 24–137 kg). Common underlying diagnoses were tetralogy of Fallot (n = 44, 33%) and pulmonary atresia +/- ventricular septal defect (n = 26, 19%). The most common previously employed conduit was a homograft (n = 91, 67%). Indications for PPVI included conduit stenosis (n = 75, 56%), regurgitation (n = 12, 9%) or mixed disease (n = 47, 35%). Immediate haemodynamic outcome was good; the peak stenotic gradient decreased from mean 40 mmHg to mean 11 mmHg (p = 0.047). Risk of severe procedural complication was low. There was one early post procedural death; due to device embolisation within the RVOT. In follow-up (median 21 months, range 0–98 months), there were two further deaths, unrelated to PPVI. Thirteen individuals developed IE (annualised incidence rate 4.6% per patient-year), 9 of these individuals required valve re-replacement. Two further individuals underwent valve replacement without IE. Conclusions: PPVI as performed in selected ANZ centres provides a relatively safe and feasible method of rehabilitating the RVOT.L20022345342019-08-01 <br />en
dc.language.isoenen
dc.relation.ispartofHeart Lung and Circulationen
dc.titlePercutaneous Pulmonary Valve Implantation (PPVI) in Australia and New Zealand (ANZ)en
dc.typeArticleen
dc.identifier.doi10.1016/j.hlc.2019.06.507en
dc.subject.keywordsmajor clinical studyen
dc.subject.keywordsmaleen
dc.subject.keywordsmorbidityen
dc.subject.keywordsmortalityen
dc.subject.keywordsmulticenter studyen
dc.subject.keywordspulmonary valve atresiaen
dc.subject.keywordsrepeat procedureen
dc.subject.keywordsretrospective studyen
dc.subject.keywordsstenosisen
dc.subject.keywordspercutaneous aortic valveen
dc.subject.keywordsadolescentadulten
dc.subject.keywordsadverse device effecten
dc.subject.keywordsallograften
dc.subject.keywordsAustralia and New Zealanden
dc.subject.keywordsbacterial endocarditisen
dc.subject.keywordschilden
dc.subject.keywordsclinical assessmenten
dc.subject.keywordscohort analysisen
dc.subject.keywordscomplicationen
dc.subject.keywordsconference abstracten
dc.subject.keywordscontrolled studyen
dc.subject.keywordsdeathen
dc.subject.keywordsdevice embolizationen
dc.subject.keywordsFallot tetralogyen
dc.subject.keywordsfemaleen
dc.subject.keywordsfollow upen
dc.subject.keywordsheart valve replacementen
dc.subject.keywordsheart ventricle septum defecten
dc.subject.keywordshemodynamicsen
dc.subject.keywordshumanen
dc.relation.urlhttps://www.embase.com/search/results?subaction=viewrecord&id=L2002234534&from=exporthttp://dx.doi.org/10.1016/j.hlc.2019.06.507 |en
dc.identifier.risid2533en
dc.description.pagesS351-S352en
item.grantfulltextnone-
item.openairetypeArticle-
item.fulltextNo Fulltext-
item.languageiso639-1en-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
Appears in Sites:Children's Health Queensland Publications
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