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Title: | Balloon Aortic Valvuloplasty for Congenital Aortic Stenosis: A 14-Year Single Centre Review | Authors: | Auld, Benjamin Carrigan, Lindsay Justo, Robert Anderson, Ben Alphonso, Nelson Ward, Cameron |
Issue Date: | 2018 | Source: | 27, (3), 2018, p. N.PAG-N.PAG | Pages: | N.PAG-N.PAG | Journal: | Heart, Lung & Circulation | Abstract: | Background: The approach to intervention for congenital aortic valve stenosis (AS) differs depending upon centre bias toward a primary catheter or surgical approach. We therefore investigated associations with freedom from re-intervention (FFI) in the cohort of children who underwent primary balloon aortic valvuloplasty (BAV) for congenital AS in our centre.Methods: All patients who underwent BAV as a primary procedure in the period between 2001 and 2015 in a single service were included. Echocardiographic parameters before and after catheterisation and procedural data was collected on all patients.Results: Sixty-four (64) patients underwent BAV as the primary intervention during the study period. Follow-up data was available for 60 of these. Balloon aortic valvuloplasty was performed at a median age of 143 days (range 2 days-18.8 years). Freedom from re-intervention was observed in 75% of patients with a median follow-up of 6.8 years and a mean follow-up of 3 years. Catheter-based peak-to-peak aortic valve gradients decreased from 58±15.9mmHg to 22.9±13.1mmHg. There was no short- or long-term mortality. FFI was predicted by aortic valve morphology (p<0.01), post-BAV mean echo gradient (p=0.03) and post-BAV regurgitation (p<0.01). No patient had re-intervention for restenosis with post-BAV mean echo gradient <30mmHg. Catheter gradients before and after BAV approached significance for predicting FFI (p=0.06 and p=0.09 respectively). Fifteen (15) patients were neonates with significantly lower aortic valve (AoV) Z-scores (mean 0.63 vs 1.76, p=0.002) and no difference in FFI (p=0.19). Annulus size, balloon/annulus ratio (within the range utilised) and pre-BAV echo findings were not predictive for re-intervention.Conclusions: Balloon aortic valvuloplasty is an effective primary approach to congenital valvular AS with the potential of avoiding surgical intervention in the majority of patients at all ages. Freedom from re-intervention in our cohort was associated with valve morphology and the degree of stenosis and regurgitation immediately post BAV.Continental Europe; Europe. Instrumentation: Foot Function Index (FFI); Short Portable Mental Status Questionnaire (SPMSQ) (Pfeiffer). NLM UID: 100963739.PMID: NLM29625867. | DOI: | 10.1016/j.hlc.2018.02.014 | Resources: | https://search.ebscohost.com/login.aspx?direct=true&AuthType=ip,athens&db=ccm&AN=129012425&site=ehost-live | Keywords: | Short Portable Mental Status Questionnaire;Aortic Valve -- SurgeryForecasting;Aortic Valve Stenosis -- Surgery;Heart Catheterization -- Methods;Balloon Dilatation -- Methods;Female;Aortic Valve Stenosis;Adolescence;Child;Retrospective Design;Aortic Valve;Infant;Infant, Newborn;Child, Preschool;Treatment Outcomes;Aortic Valve Stenosis -- Diagnosis;Male;Prospective Studies;Echocardiography | Type: | Article |
Appears in Sites: | Children's Health Queensland Publications |
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