The association between socioeconomic disadvantage and parent-rated health in children and adolescents with chronic kidney disease-the Kids with CKD (KCAD) study

Abstract

OBJECTIVE: To determine the association of socioeconomic disadvantage and parent-rated health in children with chronic kidney disease (CKD). METHODS: A total of 377 children (aged 6-18 years) with CKD stages I-V (n = 199), on dialysis (n = 43), or with a kidney transplant (n = 135) were recruited from 2012 to 2016 in Australia and New Zealand. Associations of five socioeconomic status (SES) components and the global SES index with parent-rated health of the child were examined using adjusted logistic regression. RESULTS: The median age of participants was 12.6 years (interquartile range (IQR) 8.9-15.5). In the entire cohort, the adjusted odds ratios (ORs) and 95% confidence intervals (CIs) for poor parent-rated health were 1.85 (1.13-3.03) for lower household income, 1.78 (1.08-2.96) for families that did not own their own home, 2.50 (1.50-4.16) for caregivers who rated their financial status as poor, 0.84 (0.51-1.38) for lower educational attainment, and 1.68 (1.04-2.72) for children whose primary caregivers were unemployed. With reference to the highest global SES index quartile, adjusted ORs for poor parent-rated health in descending order were 1.49 (0.69-3.21), 2.11 (1.06-4.20), and 2.20 (1.09-4.46), respectively. The association between low SES and poor parent-rated health was modified by CKD stage, where lower global SES index was independently associated with poor parent-rated health in children with CKD stages I-V, but not children on dialysis or with kidney transplants (p = 0.04). CONCLUSIONS: Low SES is associated with poor parent-rated health in children with CKD stages I-V, but not children on dialysis and with kidney transplants.1432-198xDidsbury, Madeleine <br />van Zwieten, Anita <br />Chen, Kerry <br />James, Laura J <br />Francis, Anna <br />Kim, Siah <br />McTaggart, Steven <br />Walker, Amanda <br />Mackie, Fiona <br />Kara, Tonya <br />Prestidge, Chanel <br />Teixeira-Pinto, Armando <br />Barton, Belinda <br />Lorenzo, Jennifer <br />Lah, Suncica <br />Howard, Kirsten <br />Nassar, Natasha <br />Au, Eric <br />Tong, Allison <br />Craig, Jonathan C <br />Wong, Germaine <br />Journal Article <br />Research Support, Non-U.S. Gov't <br />Germany <br />Pediatr Nephrol. 2019 Jul;34(7):1237-1245. doi: 10.1007/s00467-019-04209-7. Epub 2019 Feb 20. <br />