Please use this identifier to cite or link to this item: http://dora.health.qld.gov.au/qldresearchjspui/handle/1/930
Title: Towards a Universal Molecular Microbiological Test
Authors: Allcock, Richard J N
Jennison, Amy V
Warrilow, David 
Issue Date: 2017
Publisher: American Society for Microbiology
Source: J Clin Microbiol. 2017 Nov;55(11):3175-3182. doi: 10.1128/JCM.01155-17. Epub 2017 Aug 23.
Journal: Journal of clinical microbiology
Abstract: The standard paradigm for microbiological testing is dependent on the presentation of a patient to a clinician. Tests are then requested based on differential diagnoses using the patient's symptoms as a guide. The era of high-throughput genomic methods has the potential to replace this model for the first time with what could be referred to as "hypothesis-free testing." This approach utilizes one of a variety of methodologies to obtain a sequence from potentially any nucleic acid in a clinical sample, without prior knowledge of its content. We discuss the advantages of such an approach and the challenges in making this a reality.
DOI: 10.1128/jcm.01155-17
Keywords: communicable disease;molecular diagnosis
Type: Article
Appears in Sites:Forensic and Scientific Services

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