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https://dora.health.qld.gov.au/qldresearchjspui/handle/1/7326| Title: | Invasive fungal disease in children with solid tumors: An Australian multicenter 10-year review | Authors: | Jain, Neha Ryan, Anne L. Haeusler, Gabrielle M. McMullan, Brendan J. Moore, Andrew S. Bartlett, Adam W. Blyth, Christopher C. Kotecha, Rishi S. Yeoh, Daniel K. Clark, Julia E. |
Issue Date: | 2024 | Source: | Pediatric blood & cancer, 2024 (71) 7 p.e31031 | Pages: | e31031 | Journal Title: | Pediatric blood & cancer | Abstract: | Invasive fungal disease (IFD) occurs less frequently during treatment for solid compared to hematological malignancies in children, and risk groups are poorly defined. Retrospective national multicenter cohort data (2004-2013) were analyzed to document prevalence, clinical characteristics, and microbiology of IFD. Amongst 2067 children treated for solid malignancy, IFD prevalence was 1.9% overall and 1.4% for proven/probable IFD. Of all IFD episodes, 42.5% occurred in patients with neuroblastoma (prevalence 7.0%). Candida species comprised 54.8% of implicated pathogens in proven/probable IFD. In children with solid tumors, IFD is rare, and predominantly caused by yeasts.Routine prophylaxis may not be warranted. (© 2024 Wiley Periodicals LLC.) | DOI: | 10.1002/pbc.31031 | Resources: | https://search.ebscohost.com/login.aspx?direct=true&AuthType=ip,athens&db=mdc&AN=38679843&site=ehost-live |
| Appears in Sites: | Children's Health Queensland Publications Queensland Health Publications |
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