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Title: Extravasation injury management for neonates and children: A systematic review and aggregated case series
Authors: Dufficy, Mitchell
Takashima, Mari
Cunninghame, Jacqueline
Bronwyn Griffin 
McBride, Craig A
August, Deanne 
Ullman, Amanda 
Issue Date: 2022
Journal: Journal of hospital medicine
Abstract: Pediatric extravasation injuries are significant healthcare-associated injuries, with sometimes significant sequelae. Evidence-based guidance on management is necessary to prevent permanent injury. A systematic review of the literature, including aggregated case series, investigating extravasation injury management of hospitalized pediatric patients. PubMed, Cummulative Index to Nursing and Allied Health Literature (CINAHL), and Excerpta Medica database (EMBASE) were searched on December 13, 2021. Primary research investigating extravasation injury management of hospitalized pediatric patients (to 18 years), published from 2010 onwards and in English, independently screened by two authors, with arbitration from a third author. Data regarding the study, patient (age, primary diagnosis), extravasation (site, presentation, outcome), and treatment (first aid, wound management) were extracted by two authors, with arbitration from a third author. From an initial 1769 articles, 27 studies were included with extractable case data reported in 18 studies, resulting in 33 cases. No clinical trials were identified, instead, studies were primarily case studies (52%) of neonates (67%), with varied extravasation symptoms. Studies had good selection and ascertainment, but few met the causality and reporting requirements for quality assessments. Signs and symptoms varied, with scarring (45%) and necrosis (30%) commonly described. Diverse treatments were categorized into first aid, medical, surgical, and dressings. Despite infiltration and extravasation injuries being common within pediatric healthcare, management interventions are under-researched, with low-quality studies and no consensus on treatments or outcomes.
DOI: 10.1002/jhm.12951
Type: Article
Appears in Sites:Children's Health Queensland Publications

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