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https://dora.health.qld.gov.au/qldresearchjspui/handle/1/4054| Title: | Pediatric transplantation: Preventing thrombosis | Authors: | Robertson, J. D. | Issue Date: | 2015 | Source: | 13, (S1), 2015, p. S351-S361 | Pages: | S351-S361 | Journal: | Journal of Thrombosis and Haemostasis | Abstract: | Due to progressive advances in surgical techniques, immunosuppressive therapies, and supportive care, outcomes from both solid organ transplantation and hematopoietic stem cell transplantation continue to improve. Thrombosis remains a challenging management issue in this context, with implications for both graft survival and long-term quality of life. Unfortunately, there remains a general paucity of pediatric-specific data regarding thrombosis incidence, risk stratification, and the safety or efficacy of preventative strategies with which to guide treatment algorithms. This review summarizes the available evidence and rationale underlying the spectrum of current practices aimed at preventing thrombosis in the transplant recipient, with a particular focus on risk factors, pathophysiology, and described antithrombotic regimens.L6049397532015-06-26 | DOI: | 10.1111/jth.12968 | Resources: | https://www.embase.com/search/results?subaction=viewrecord&id=L604939753&from=exporthttp://dx.doi.org/10.1111/jth.12968 | | Keywords: | heparin;low molecular weight heparin;plasminogen;protein C;protein S;blood transfusion;cardiopulmonary bypass;child care;clinical effectiveness;graft recipient;graft survival;heart disease;heart transplantation;hematopoietic stem cell transplantation;hepatic artery thrombosis;high risk population;human;incidence;international normalized ratio;intracardiac thrombosis;kidney transplantation;liver disease;liver transplantation;organ transplantation;outcome assessment;pathophysiology;patient monitoring;pediatric surgery;portal vein thrombosis;prevalence;priority journal;prosthesis thrombosis;quality of life;review;dipyridamole;shunt thrombosis;surgical risk;thrombosis;thrombosis prevention;clopidogrel;blood clotting factor 8;antithrombin;risk assessment;ventricular assist deviceacetylsalicylic acid | Type: | Article |
| Appears in Sites: | Children's Health Queensland Publications |
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