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Title: | Over-diagnosis of rotavirus infection in infants due to detection of vaccine virus | Authors: | Clark, J. E. Nimmo, G. R. Grimwood, K. Lambert, S. B. Bletchly, C. Whiley, D. M. Ye, S. Tozer, S. |
Issue Date: | 2020 | Source: | 71, (5), 2020, p. 1324-1326 | Pages: | 1324-1326 | Journal: | Clinical Infectious Diseases | Abstract: | An accurate rotavirus diagnosis is important for clinical management and monitoring active disease and vaccine effectiveness. Between 2016-2018, rotavirus-positive results in our laboratory were from vaccine virus shedding in 71/152 (46.7%) infants with a request for rotavirus testing. Routine infant diagnostic testing should ideally distinguish vaccine from wild-type viruses.L20084152142020-11-05 | DOI: | 10.1093/cid/ciz1196 | Resources: | https://www.embase.com/search/results?subaction=viewrecord&id=L2008415214&from=exporthttp://dx.doi.org/10.1093/cid/ciz1196 | | Keywords: | nonhuman;priority journal;reverse transcription polymerase chain reaction;Rotavirus;vaccination;virus detection;virus shedding;Rotavirus infection;polymerase chain reaction systemrotarix rv 1;rotateq rv 5;Rotavirus vaccine;adolescent;adult;aged;article;child;cohort analysis;controlled study;diagnostic accuracy;diagnostic error;diagnostic test;diagnostic test accuracy study;female;human;infant;major clinical study;male;newborn | Type: | Article |
Appears in Sites: | Children's Health Queensland Publications |
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