Managing and weaning home oxygen in chronic neonatal lung disease

Abstract

Introduction/Aim: In 2005, Australia and Queensland had 20127 and 7670 patients respectively on home oxygen with chronic neonatal lung disease (CNLD) being the most common paediatric indication. No consensus guidelines exist for weaning home oxygen in CNLD including overnight oximetry interpretation. We aim to describe our approach and outcomes to managing home oxygen in CNLD. Methods: A retrospective review of all overnight oximetries for infants under 2 years old with primary diagnosis of CNLD received by the Paediatric Respiratory and Sleep Department over a 12 month period. Results: 191 overnight oximetry studies from 79 infants were identified within a 12 month period. 47 infants were weaned off oxygen at a median 24 weeks (IQR 18) post-menstrual age. Median PaCO2 at term corrected age was 52 (IQR 9). Specific follow-up findings are outline in table 1. Conclusion: Overnight oximetry is used extensively to guide home oxygen weaning despite the limited evidence for interpretation of oximetry studies in this population. Most studies were undertaken at home suggesting that this is a valid method of monitoring infants. There was a highly varied follow-up frequency and oximetry evaluation post-hospital discharge. Preliminary analyses have not shown any specific patient or oximetry parameters that can reliably predict timing of successful home oxygen wean. Further data analysis is underway and key findings to be presented. (Figure Presented).L6269400932019-04-02 <br />