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https://dora.health.qld.gov.au/qldresearchjspui/handle/1/3036| Title: | Focal segmental glomerulosclerosis associated with acute cytomegalovirus infection in a renal transplant | Authors: | Burke, J. Wynd, E. Stewart, A. |
Issue Date: | 2019 | Source: | 23, (6), 2019 | Journal: | Pediatric Transplantation | Abstract: | Focal segmental glomerulosclerosis (FSGS) occurring in association with cytomegalovirus (CMV) infection in a renal transplant patient with no previous history of FSGS has rarely been reported. We present a case of a 16-year-old renal transplant recipient who developed acute hepatitis, leukopenia, nephrotic syndrome, and progressive renal dysfunction in the setting of acute infection with CMV. The cytomegalovirus infection was successfully treated with IV ganciclovir followed by oral valganciclovir but renal function deterioration and massive proteinuria continued. Features of FSGS were found on two renal allograft biopsies. Plasmapheresis and cyclophosphamide treatment was instituted with no clear effect on disease progress.L6284313242019-07-12 | DOI: | 10.1111/petr.13538 | Resources: | https://www.embase.com/search/results?subaction=viewrecord&id=L628431324&from=exporthttp://dx.doi.org/10.1111/petr.13538 | | Keywords: | adolescent;alanine aminotransferase blood level;albumin blood level;article;aspartate aminotransferase blood level;biopsy;brain death;case report;Caucasian;clinical article;creatinine clearance;cytomegalovirus infection;disease association;erythrocyte count;failure to thrive;focal glomerulosclerosis;follow up;human tissue;immunosuppressive treatment;kidney transplantation;kidney tubule disorder;leukocyte count;leukopenia;liver dysfunction;male;nonhuman;peritoneal dialysis;platelet count;polymerase chain reaction;prophylaxis;urinalysis;virus load;vesicoureteral reflux;gamma glutamyl transferase blood level;hepatitis;hospital discharge;human;albuminaspartate aminotransferase;basiliximab;erythrocyte antibody;gamma glutamyltransferase;ganciclovir;lactate dehydrogenase;methylprednisolone;mycophenolic acid;prednisolone;tacrolimus;valganciclovir | Type: | Article |
| Appears in Sites: | Children's Health Queensland Publications |
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