Comparative global epidemiology of influenza, respiratory syncytial and parainfluenza viruses, 2010-2015

Abstract

Objectives: To improve our understanding of the global epidemiology of common respiratory viruses by analysing their contemporaneous incidence at multiple sites.; Methods: 2010-2015 incidence data for influenza A (IAV), influenza B (IBV), respiratory syncytial (RSV) and parainfluenza (PIV) virus infections were collected from 18 sites (14 countries), consisting of local (n = 6), regional (n = 9) and national (n = 3) laboratories using molecular diagnostic methods. Each site submitted monthly virus incidence data, together with details of their patient populations tested and diagnostic assays used.; Results: For the Northern Hemisphere temperate countries, the IAV, IBV and RSV incidence peaks were 2-6 months out of phase with those in the Southern Hemisphere, with IAV having a sharp out-of-phase difference at 6 months, whereas IBV and RSV showed more variable out-of-phase differences of 2-6 months. The tropical sites Singapore and Kuala Lumpur showed fluctuating incidence of these viruses throughout the year, whereas subtropical sites such as Hong Kong, Brisbane and Sydney showed distinctive biannual peaks for IAV but not for RSV and PIV.; Conclusions: There was a notable pattern of synchrony of IAV, IBV and RSV incidence peaks globally, and within countries with multiple sampling sites (Canada, UK, Australia), despite significant distances between these sites. (Copyright © 2019. Published by Elsevier Ltd.)Epidemiol Infect. 2016 Mar;144(4):751-67. (PMID: 26345289); BMC Infect Dis. 2016 Dec 19;16(1):762. (PMID: 27993136); J Infect Dis. 2012 Dec 15;206 Suppl 1:S74-9. (PMID: 23169976); Influenza Other Respir Viruses. 2018 May;12(3):383-411. (PMID: 29127742); PLoS One. 2017 May 25;12(5):e0177655. (PMID: 28542324); PLoS Med. 2009 Nov;6(11):e1000168. (PMID: 19918363); Clin Microbiol Infect. 2015 Sep;21(9):861-6. (PMID: 26033670); Ital J Pediatr. 2009 Jun 25;35:16. (PMID: 19555507); PLoS One. 2012;7(11):e48609. (PMID: 23139802); Lancet Infect Dis. 2017 Oct;17(10):e320-e326. (PMID: 28457597); Am J Infect Dis. 2013;9(3):77-93. (PMID: 26561480); Infect Genet Evol. 2017 Apr;49:241-250. (PMID: 28132927); BMC Infect Dis. 2018 Dec 27;18(1):695. (PMID: 30587159); Arch Dis Child. 2018 Jan;103(1):101-105. (PMID: 28855230); BMC Infect Dis. 2018 Mar 6;18(1):111. (PMID: 29510663); Rev Med Virol. 2014 Jan;24(1):15-34. (PMID: 24421259); PLoS One. 2014 Oct 23;9(10):e110713. (PMID: 25340711); Influenza Other Respir Viruses. 2019 Mar;13(2):138-147. (PMID: 30596225); BMC Infect Dis. 2015 Oct 24;15:447. (PMID: 26497393); Lancet. 2010 May 1;375(9725):1545-55. (PMID: 20399493); BMC Infect Dis. 2013 Jan 23;13:28. (PMID: 23343342); Annu Rev Genomics Hum Genet. 2016 Aug 31;17:193-218. (PMID: 27216777); J Med Virol. 2019 Mar;91(3):498-502. (PMID: 30199092); PLoS One. 2013;8(2):e54445. (PMID: 23457451); Semin Respir Crit Care Med. 2007 Apr;28(2):182-92. (PMID: 17458772); J Infect Dis. 2018 Apr 11;217(9):1356-1364. (PMID: 29390105); J R Soc Interface. 2015 Nov 6;12(112):. (PMID: 26559683). Linking ISSN: 01634453. Subset: MEDLINE; Date of Electronic Publication: 2019 Jul 16. Current Imprints: Publication: Kent, UK : W.B. Saunders; Original Imprints: Publication: London, New York, Academic Press. <br />