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Title: | Hypertension, Left Ventricular Hypertrophy, and Myocardial Ischemia | Authors: | Stanton, T. Dunn, F. G. |
Issue Date: | 2017 | Source: | 101, (1), 2017, p. 29-41 | Pages: | 29-41 | Journal: | Medical Clinics of North America | Abstract: | The risks associated with hypertension emerge through a series of complex interactions. Myocardial ischemia is the major contributor to this risk. The mechanisms driving ischemia reflect many of the key factors in hypertension, including endothelial and neurohumoral factors, fibrosis, and hemodynamics. Left ventricular hypertrophy and fibrosis are of fundamental importance and together with hemodynamics provide an optimal template for myocardial ischemia. Understanding the pathophysiology has aided a more rational management approach but challenges remain which, if surmounted, will have an impact on the morbidity and mortality caused by myocardial ischemia in patients with hypertension.L613410925 | DOI: | 10.1016/j.mcna.2016.08.003 | Resources: | http://www.embase.com/search/results?subaction=viewrecord&from=export&id=L613410925http://dx.doi.org/10.1016/j.mcna.2016.08.003 http://linksource.ebsco.com/ls.b6e6cc08-c492-42af-aec4-c6084e18e68c.true/linking.aspx?sid=EMBASE&issn=15579859&id=doi:10.1016%2Fj.mcna.2016.08.003&atitle=Hypertension%2C+Left+Ventricular+Hypertrophy%2C+and+Myocardial+Ischemia&stitle=Med.+Clin.+North+Am.&title=Medical+Clinics+of+North+America&volume=101&issue=1&spage=29&epage=41&aulast=Stanton&aufirst=Tony&auinit=T.&aufull=Stanton+T.&coden=MCNAA&isbn=&pages=29-41&date=2017&auinit1=T&auinitm= |
Keywords: | aldosterone antagonistamlodipine;angiotensin receptor antagonist;arginine;benidipine;beta adrenergic receptor blocking agent;C reactive protein;dipeptidyl carboxypeptidase inhibitor;felodipine;interleukin 6;ranolazine;tumor necrosis factor;angina pectoris;apoptosis;arterial stiffness;heart muscle cell;cardiovascular magnetic resonance;cardiovascular mortality;cardiovascular risk;clinical feature;computer assisted tomography;coronary artery disease;disease association;disease classification;disease predisposition;echocardiography;electrocardiography;endothelial dysfunction;heart afterload;heart hemodynamics;heart hypertrophy;heart left ventricle hypertrophy;heart muscle fibrosis;heart muscle ischemia;heart ventricle remodeling;human;hypertension;morbidity;nonhuman;pathophysiology;positron emission tomography;priority journal;review;risk factor;sudden cardiac death | Type: | Article |
Appears in Sites: | Sunshine Coast HHS Publications |
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