https://dora.health.qld.gov.au/qldresearchjspui/handle/1/11262 Sun, 20 Sep 2026 22:21:50 GMT 2026-09-20T22:21:50Z https://dora.health.qld.gov.au/qldresearchjspui/handle/1/12365 Title: Collaborative General Practitioner Shared Care Versus Self-Directed Care Following Critical Illness in Young Children: A Pilot Hybrid Effectiveness-Implementation Randomized Controlled Trial Authors: Long, Debbie A; Tyack, Zephanie; Anthony, Lori; Dow, Belinda; Dunn, Leigh; Le Marsney, Renate; Pham, Trang M T; Best, James; Webb, Kerri-Lyn; Liley, Helen; Stocker, Christian; Thoms, Debra; Schlapbach, Luregn J; Moore, Charlotte; Lister, Paula; Bora, Samudragupta; Gibbons, Kristen Abstract: Up to one in three PICU survivors experience persistent developmental or psychologic challenges, and parents often report significant psychologic distress. Current health systems lack standardized pathways to support children and families after PICU. We aimed to assess the feasibility of a randomized controlled trial (RCT) of a collaborative general practitioner (GP) shared-care follow-up model of care intervention and the feasibility, acceptability, and appropriateness of the intervention. Multicenter, pilot, hybrid effectiveness-implementation study with parallel RCT. Trial registration: Australian and New Zealand Clinical Trials Registry, ACTRN12621000799853, June 24, 2021. Two PICUs in Queensland, Australia. Parents of children admitted to PICU from ages 2 months or older to younger than 4 years. Participants were randomized (1:1, web-based block randomization schedule) to 6 months of GP shared care (intervention) or self-directed care (active control). The primary outcome was trial feasibility. Secondary effectiveness and implementation outcomes included child neurodevelopmental vulnerability and parent psychosocial outcomes at 6 months and parental perception of the feasibility, acceptability, and appropriateness of the intervention, respectively. Between October 2021 and March 2023, 154 of 363 eligible parents (one per family) provided consent (42%); 69 were randomized to the intervention, and 72 to active control. Most parents were mothers (95%), 31-40 years old (54%), from metropolitan areas (72%). Children were predominantly male (64%), younger than 12 months old (41%), admitted for respiratory illness (39%). Retention (81%), fidelity (96%), and intervention acceptability was high (71-86%), but recruitment was low (42%) and intervention feasibility varied (35-82%). At 6 months, neurodevelopmental vulnerability rates were similar (shared care [39%] vs. active control [44%]; adjusted odds ratio (aOR), 0.72 [95% CI, 0.32-1.60]). Parenting stress was lower in the intervention group (median, 20 [interquartile range (IQR), 12-47]) vs. active control (median, 42 [IQR, 19-66]; difference, -23 [95% CI, -40 to -6]). A trial of a collaborative GP-shared-care model of care post-PICU is feasible and may reduce parenting stress. Further intervention refinement and a larger trial are warranted to evaluate clinical effectiveness, implementation, and scalability. Wed, 26 Aug 2026 00:00:00 GMT https://dora.health.qld.gov.au/qldresearchjspui/handle/1/12365 2026-08-26T00:00:00Z https://dora.health.qld.gov.au/qldresearchjspui/handle/1/11327 Title: Queensland paediatric sepsis mortality study Authors: Queensland Family and Child Commission (QFCC), Queensland Paediatric Sepsis Program (QPSP) Thu, 01 Feb 2024 00:00:00 GMT https://dora.health.qld.gov.au/qldresearchjspui/handle/1/11327 2024-02-01T00:00:00Z https://dora.health.qld.gov.au/qldresearchjspui/handle/1/11326 Title: Research annual report: Sepsis pathway improves time to treatment for sickest kids Authors: Harley, Amanda Thu, 01 Dec 2022 00:00:00 GMT https://dora.health.qld.gov.au/qldresearchjspui/handle/1/11326 2022-12-01T00:00:00Z https://dora.health.qld.gov.au/qldresearchjspui/handle/1/11325 Title: Research annual report: Researcher profile: Dr Adam Irwin | A global leader in paediatric sepsis research: Dr Amanda Harley Authors: Adam D Irwin Thu, 01 Jul 2021 00:00:00 GMT https://dora.health.qld.gov.au/qldresearchjspui/handle/1/11325 2021-07-01T00:00:00Z